Vitamin B12 deficiency in general practice: HealthCert GP Update, 2026

In this HealthCert GP Update, Dr Simone Gonzo guides you through how to recognise, investigate, and manage vitamin B12 deficiency in primary care, including how to interpret borderline results, when to use MMA and homocysteine testing, and how to avoid common diagnostic pitfalls — providing a clear, practical overview tailored for busy GPs.

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Full GP Update video

Below, watch the full expert presentation and Q&A with Dr Simone Gonzo.

What you will learn

Many patients with vitamin B12 deficiency don’t present with “classic" symptoms. Instead, they come in with fatigue, cognitive change, neuropathy, mood symptoms, or vague complaints that can easily be overlooked in everyday practice.

In this HealthCert GP Update webinar, Dr Simone Gonzo guides you through:

• Common causes of B12 deficiency, including pernicious anaemia, medications, malabsorption, and dietary factors
• When neurological symptoms should raise concern
• Oral vs intramuscular replacement strategies
• Monitoring and long-term management
• New Medicare item changes relevant to B12 testing 

This webinar builds naturally on our previous iron deficiency session and will help GPs approach another commonly missed but clinically significant nutritional deficiency with greater confidence.

Next steps in your learning journey

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Explore more GP Updates

Watch the full HealthCert GP Update webinar series here.

Podcast playlist

Listen to all episodes in the HealthCert GP Update series on-the-go.

About the presenter

Dr Simone Gonzo began working in healthcare as a registered nurse in hospitals throughout Queensland in 2003. After making the change to medicine, she graduated with an MBBS from The University of Queensland in 2010 and gained FRACGP in 2015. Dr Gonzo enjoys all aspects of general practice including family health, mental health, chronic disease management, and complex primary care. She also has a special interest in teaching and training GP registrars and medical students. Dr Gonzo is a champion of general practice and promotes the importance of this specialty in the healthcare landscape.

CPD self-submission

You can self-record CPD for this HealthCert GP Update. If you consume educational content on this blog, you can Quick Log CPD hours with the RACGP/ACRRM via the usual self-submission process. You will be asked to reflect on what you have learned, and you will require supporting evidence such as a screenshot. For more information, view the: RACGP CPD guide | ACRRM CPD guide

[coming soon] Bonus GP Update resources

Make it easier to apply these guidelines in practice with additional resources:

• Key takeaways factsheet: Download a one-page summary for quick reference. Download factsheet >
• FAQ guide: The most common questions from GPs in the live session, answered by Dr Simone Gonzo. Download Q&A summary >
• Podcast episode: Listen to the update on the go >